Calcium deficiency in adults can have the following clinical symptoms: First, muscle spasms. Patients with hypocalcemia can have spasms of the face, back, and thigh and calf muscles, especially at night when they sleep and when they are cold, and muscle spasms are very pronounced, often with convulsions. Secondly, twitching, spasms or seizures of the throat, hands and feet, which can also be accompanied by facial spasms. Third, sensory disturbances, there can be numbness and tingling of the tongue, palms and feet. Fourth, facial nerve percussion signs. When the facial nerve is gently tapped, there may be twitching at the corners of the eyes and mouth, which is a manifestation of facial nerve percussion signs. Fifth, nail and skin changes, the nails can become brittle, the skin can become dry, with scaling symptoms. Sixth, neurological symptoms, neurological symptoms include depression, anxiety, drowsiness and other symptoms. Patients with hypocalcemia should be examined early and treated with calcium supplementation early to avoid serious consequences.