High homocysteine does not cause hypertrophic cardiomyopathy. Hypertrophic cardiomyopathy, also known as hypertrophic cardiomyopathy, is a hereditary cardiomyopathy, a heart disease characterized by asymmetric hypertrophy of the ventricles. Its common symptoms include exertional dyspnea, chest pain, panic, syncope, chest tightness, and weakness. The disease can be clinically divided into obstructive hypertrophic cardiomyopathy and non-obstructive hypertrophic cardiomyopathy. Hypertrophic cardiomyopathy is autosomal dominant, with a clear tendency of familial onset, and homocysteine is a sulfur-containing amino acid, whose high blood concentration may increase the risk of cardiovascular and cerebrovascular diseases, such as coronary heart disease and stroke. This shows that elevated homocysteine does not usually cause hypertrophic cardiomyopathy. If patients are diagnosed with hypertrophic cardiomyopathy, they should go to regular hospitals in time and receive standardized treatment under the guidance of professional doctors in order to reduce the adverse effects of the disease.