Progressive lung adenocarcinoma has a high possibility of metastasis, which is over 90%. Progressive lung adenocarcinoma means that the patient’s cancer is in continuous development and deterioration, and most of the patients have already entered the middle and late stages, and started to have metastasis and spreading of lymph nodes and distal organs, with the possibility of metastasis above 90%, which should be determined according to the type of pathology, physical condition and so on. Progressive lung adenocarcinoma must be treated timely with surgery, radiotherapy, chemotherapy and other targeted treatments. If the treatment is not timely, the condition will deteriorate in a short time and rapidly enter into the advanced stage, resulting in the death of the patient; while active treatment can control the condition well and prolong the survival period of the patient.