Severe pustular pimples can be treated with medication, surgery or other methods. 1. Drug treatment: pustular pimples, but no liquid exudate can choose tincture of iodine disinfection, topical application of mupirocin ointment, such as liquid exudate, and then use boric acid solution wet compress. If the scope of lesions is large, oral minocycline capsules anti-inflammatory. 2. Surgical treatment: larger pustular acne is generally recommended as soon as possible incision and drainage, the purulent secretions cleaned up and then coated with erythromycin ointment, mupirocin ointment. 3. Other methods: pustule pimples in the volume is relatively large, red, swollen, pain and other symptoms, it is recommended to take physical therapy, such as ultra-short-wave physiotherapy, infrared physiotherapy and so on. After the detection of pustular pimples, we should pay attention to the skin surface hygiene, specific medication should follow the doctor’s instructions.