Hypertension refers to high diastolic blood pressure. Simple diastolic hypertension is commonly seen in young and middle-aged hypertensive male patients aged 20 to 50 years old, mostly with insidious onset. These patients often have poor lifestyles such as high work stress, mental tension, long working hours, obesity, alcohol consumption, smoking, sedentary lifestyle, and high salt diet. Treatment should be with antihypertensive medication supplemented with lifestyle interventions. The criteria for high diastolic blood pressure are at least three non-same day blood pressure measurements with diastolic blood pressure ≥ 90 mm Hg. Cerebral ischemia, high salt diet, and stress all lead to sympathetic excitation, promote the release of norepinephrine, and activate the renin-angiotensin-aldosterone system, causing vasoconstriction and increased peripheral resistance, resulting in increased diastolic blood pressure. The treatment of high diastolic blood pressure alone should be β-blockers as the first choice, followed by angiotensin-converting enzyme inhibitors and angiotensin receptor antagonist drugs. If the effect of antihypertensive drugs is not satisfactory, you should go to the cardiology department of the hospital and ask the specialist to adjust the antihypertensive drugs. If the blood pressure can still be maintained at a normal level, it is ideal to maintain normal blood pressure at the lowest dose, but do not stop the medication easily. Adhere to the drug treatment at the same time to adjust the lifestyle, limit smoking and alcohol, increase physical exercise.