If the blood glucose does not decrease after taking long-acting insulin, patients need to increase the dosage, supplement with oral medication or change the type of insulin under the guidance of doctor, and pay attention to controlling the daily diet at the same time. 1. Adjust the dose or change the type of insulin: insulin is divided into short-acting, intermediate-acting and long-acting types. If the blood glucose does not decrease with long-acting insulin, you can increase the dose or change the type of insulin under the guidance of the doctor, and monitor the changes of blood glucose at regular intervals. 2. Supplemented with oral medication: some patients do not lower their blood glucose with long-acting insulin, which may be due to factors such as obesity, which reduces the sensitivity of the body to insulin and causes insulin resistance. At this time, patients can take oral metformin and other drugs under the guidance of the doctor to enhance the effect of lowering sugar. 3. Control daily diet: Although people with high blood glucose can control their blood glucose by oral hypoglycemic drugs and insulin injections, they also need to control their daily diet. If the patients don’t pay attention to dietary control, even if they are injecting insulin, their blood glucose may not be lowered. It is recommended that patients pay attention to reducing the intake of sugary and starchy foods in their daily diet. There are many reasons why patients’ blood glucose does not decrease when they take long-acting insulin, so it is recommended that patients should consult a doctor in time to find out the specific reasons.