The basic principle of corneal transplantation: Corneal transplantation is a procedure where the diseased corneal tissue is removed and replaced with a clear, functional cornea. Depending on the location of the corneal lesion, if it is in the center, then only the central portion is replaced; if it is located at the edge of the cornea, then replacing the cornea with the edge lesion is sufficient. For corneal-related diseases, see the corresponding pages on this website: keratitis, keratoconus, and ocular trauma. With the development of science and technology, corneal transplantation has become a very successful transplantation procedure, and its surgical results are the best among all organ transplants. For some patients with good corneal conditions, the success rate of corneal transplantation reaches more than 90%, and most patients with corneal blindness can regain useful vision through corneal transplantation. Indications for corneal transplantation: Indications for corneal transplantation: corneal diseases that cloud the cornea from clear to cloudy and affect vision, such as corneal leukoplakia, corneal opacity, cone corneas, glaucoma or IOL surgery caused by herpetic keratopathy, corneal dystrophy, certain types of corneal ulcers, etc. Source of corneal transplant material: The donor corneas used for corneal transplantation are donated by others. Generally, healthy individuals between the ages of 6 and 60 are suitable corneal donors. If the donor cornea has a history of surgery, or has glaucoma or has an eye tumor, it is not suitable. Currently, some major cities in China have established their own eye banks and are enabling more corneal blind patients to receive corneal transplants. The eye bank in Shanghai is located at the Shanghai Tenth People’s Hospital. The central mission of the eye bank is to collect, preserve and study corneal materials and other eye tissues to provide corneal materials for corneal transplants and other surgeries in a timely and reasonable manner to meet the needs of the majority of blind patients. Post-transplantation precautions: Surgery is only part of corneal transplantation, post-operative management and self-care are equally important elements of corneal transplantation that cannot be ignored. 1. Regular review; 2. Corneal suture removal time is determined by the doctor. If the patient has good vision when the sutures exist and the corneal topography behaves regularly, the sutures can be considered to be retained for a long period of time because the removal of the sutures may change the curvature of the cornea, thus causing significant astigmatism and resulting in a significant decrease in vision after the removal of the sutures; 3. Pay attention to the occurrence of rejection reaction. Rejection reactions often occur within 6 months after surgery, but they have also occurred in some patients for several years after surgery. Therefore, if the patient feels eye redness, pain, sudden vision loss, and the corneal graft becomes cloudy, go to the hospital immediately, and if possible, it is better to go back to the surgery hospital for follow-up; 4, safe and effective eye drops. Note that the dropper tip should not touch the corneal graft; more than two kinds of eye drops should be used alternately, a few minutes apart each time, to ensure the concentration of drugs in the eye; 5, reasonable diet. Proper nutrition to enhance body resistance; eat more fruits and vegetables to keep bowel movements smooth; eat less spicy and greasy food; 6. Pay attention to activities and rest. Pay attention to eye hygiene, do not rub your eyes; wear protective glasses when you go out to avoid touching the operated eye. The nerve perception of the transplanted piece has not yet been established within one year, so it is senseless and easily injured, so pay attention to avoid friction. If you are a patient with herpes simplex virus infection, you should pay attention to prevent cold, upper respiratory tract infection and overwork after surgery, and do not smoke to prevent recurrence of keratitis.