Novel Coronavirus Pneumonia is an acute infectious pneumonia that presents with different symptoms as the disease progresses, and some infected individuals may not present with significant clinical manifestations, only when the nucleic acid test for Novel Coronavirus is positive. Mild manifestations such as fever, dry cough, nasal congestion, sore throat, malaise, and muscle aches are predominant in vaccinated persons, while some infected persons may not show symptoms, and mildly ill patients usually have no pneumonia manifestations. As well as most of the mild patients may have nasal congestion, sore throat, loss of smell and taste, accompanied by conjunctivitis, myalgia, diarrhea and other manifestations. As the disease progresses, severe patients will develop respiratory distress within a week or so of onset, and the more severe cases will rapidly cause acute respiratory distress syndrome, metabolic acidosis, septic shock, and even multi-organ failure. New coronavirus pneumonia, if diagnosed or suspected, especially the existence of underlying medical history, need to be reported in a timely manner, take the initiative to isolate. Tip: In this article, “new coronavirus pneumonia” and “new coronavirus pneumonia” were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.