A pimple under the armpit, which can squeeze out white discharge, is considered as a possible skin boil or carbuncle, and the treatment includes local medication, systemic medication, and surgery. Skin boils are acute purulent inflammation of the deeper parts of the skin follicles and surrounding tissues, often induced by Staphylococcus aureus, and can form hard nodules under the skin, with yellowish-white punctate pus plugs at the top. When multiple boils are aggregated and fused, carbuncles may form, which may reach the subcutaneous tissue. If the boil is not suppurated in the early stage, it can be treated with 20% ichthyol ointment and mupirocin ointment topically. If it progresses to skin carbuncle, with large redness and swelling and much necrotic tissue in the central part, surgical treatment is feasible, with incision and drainage of the skin carbuncle, use of gauze tamponade in the wound, and regular wound dressing change. Systemic treatment can choose penicillin (amoxicillin), cephalosporin (ceftazidime), macrolides (erythromycin) and other antibiotics, anti-infection treatment. When the above symptoms appear, it is recommended to consult a doctor in time and standardize the treatment under the doctor’s guidance. Drugs need to be used as prescribed by the doctor, do not self-medicate.