Both rabeprazole and omeprazole are proton pump inhibitors, and in theory, rabeprazole has a stronger acid-suppressing effect than omeprazole. However, it also depends on the specifications of the two drugs and the dose that the patient takes orally. It also depends on the patient’s own sensitivity to the drug. Some people may have better results with oral omeprazole, while others have better results with rabeprazole. Therefore, the best drug is the one that suits you and is not based on cost. People with gastric problems are recommended to prefer omeprazole treatment, unless there is a contraindication to taking omeprazole, then other proton pump inhibitors should be considered. Specific drug usage and dosage requires consultation with a specialist, and can be combined with gastric mucosal protective agents for the treatment of gastric disease if necessary.