Factors related to type 1 diabetes 1. Autoimmune system defects: Because a variety of autoimmune antibodies can be detected in the blood of type 1 diabetes patients, such as glutamic acid decarboxylase antibodies (GAD antibodies) and islet cell antibodies (ICA antibodies). These abnormal autoantibodies can damage the insulin-secreting B cells of human pancreatic islets, so that they cannot secrete insulin normally. 2, genetic factors: current research suggests that genetic defects are the basis for the development of type 1 diabetes, and this genetic defect is manifested in the abnormal HLA antigens of the sixth pair of human chromosomes. Scientists’ research suggests that type I diabetes has a familial onset, and if your parents have diabetes, then you are more likely to develop the disease compared to people without such a family history. 3, viral infection: may be the cause, perhaps to your surprise, many scientists suspect that viruses can also cause type I diabetes. This is because people with type I diabetes often have had viral infections for some time before the onset of the disease, and the “epidemic” of type I diabetes often occurs after a virus epidemic. Viruses, such as those that cause mumps and rubella, and the coxsackievirus family, which causes polio, can play a role in type I diabetes. 4, other factors: such as milk, oxygen free radicals, some rodenticides, etc. Whether these factors can cause diabetes is being studied by scientists. Factors related to type 2 diabetes 1, genetic factors: similar to type 1 diabetes, type 2 diabetes also has a family onset. Therefore it is likely to be related to genetic inheritance. This genetic trait is more pronounced in type 2 diabetes than in type 1 diabetes. For example, if one of the twins has type 1 diabetes, the other one has a 40% chance of developing the disease; but if it is type 2 diabetes, the other one has a 70% chance of developing type 2 diabetes. 2, obesity: an important factor of type 2 diabetes may be obesity. Genetic reasons can cause obesity, the same can also cause type 2 diabetes. The body center type obese patient’s excess fat concentrated in the abdomen, they are more likely to occur than those fat concentrated in the buttocks and thighs type 2 diabetes. 3, age: age is also a factor in the development of type 2 diabetes. Half of the type 2 diabetes patients more than 55 years old after the onset. Older patients are also prone to diabetes and older people tend to be overweight. 4, modern lifestyle: eating high-calorie food and reduced exercise can also cause diabetes, which some people believe is also caused by obesity. Obesity and type 2 diabetes, as in those who have “westernized” diet and activity habits of Asian Americans and Latin American businessmen are more common. Factors related to gestational diabetes 1, hormone abnormalities: pregnancy placenta will produce a variety of hormones for fetal development and growth, these hormones are very important to the healthy growth of the fetus, but can block the role of insulin in the mother’s body, and therefore cause diabetes. The 24th to 28th cycle of pregnancy is the peak period of these hormones, and is also the frequent time of gestational diabetes. 2. Genetic basis: Patients who develop gestational diabetes have a high risk of developing type 2 diabetes in the future (but not associated with type 1 diabetes). Therefore, some people think that the gene that causes gestational diabetes and the gene that causes type 2 diabetes may be related to each other. 3, obesity: obesity is not only easy to cause type 2 diabetes, but also can cause gestational diabetes.