Generalized bone pain may be a precursor of osteoporosis, rheumatoid arthritis and other diseases. 1. Osteoporosis: Osteoporosis patients due to the loss of calcium, will lead to the symptoms of generalized bone pain, which most often occurs in elderly women. It is mainly related to the decrease of estrogen secretion and calcium loss in old age, which is manifested as bone pain during activity or exercise. 2. Rheumatoid arthritis: Rheumatoid arthritis can involve the joints of the whole body, which leads to the symptoms of generalized bone pain, with joint pain as the main manifestation. In addition, excessive exercise, cold, tumor bone metastasis, etc. can also appear the symptoms of generalized bone pain. If you are experiencing generalized bone pain, you should go to a regular hospital to get a clear picture of the cause of the disease and follow the doctor’s instructions for treatment.