The vast majority of patients with thyroid nodules have no clinical symptoms and are often detected by physical examination or by their own touch or imaging. When the nodule compresses the surrounding tissues, the corresponding clinical manifestations may appear, such as hoarseness, breath-holding, dysphagia and so on. When combined with hyperthyroidism (hyperthyroidism), the corresponding clinical manifestations of hyperthyroidism, such as rapid heartbeat, often accompanied by panic, excessive sweating, hand tremor, etc., may appear. High-definition thyroid ultrasonography is the most sensitive method of evaluating thyroid nodules. It can be used not only for discerning the nature of nodules, but also for ultrasound-guided thyroid fine needle aspiration and cytology. Patients with thyroid nodules are recommended to be seen by a physician.