Regular use of insulin by diabetic patients under doctor’s guidance will generally not affect liver function or cause liver damage. Insulin is a hypoglycemic drug, and the commonly used dosage form is injection, including Glycine Insulin Injection, Dieter’s Insulin Injection, Lysine Insulin Injection, Menthol Insulin Injection and other dosage forms, which are mainly used in the treatment of diabetes. Insulin itself mimics the body’s normal endogenous insulin secretion and plays a role in lowering glucose, with no damage to the liver. For diabetic patients with hepatic and renal impairment, insulin can be used to control blood glucose under the guidance of a physician, but it should be contraindicated for those who are allergic to insulin, and those with hypoglycemia and pancreatic islet cell tumors.