Swelling of the calves in this case should first be asked about the patient’s past medical history, and if the patient has high blood pressure, it is important to ask which medication is currently being taken. Some antihypertensive drugs themselves can cause swelling of the calves, like calcium channel blockers; relatively common antihypertensive drugs that can trigger ankle edema, representative drugs are amlodipine, felodipine; some people may be currently taking oral glucocorticosteroids, which may also cause swelling of the calves; some people may have had heart failure, renal insufficiency, or acute myocardial infarction, which may also cause swelling of the calves; and some people may have heart failure, renal insufficiency, or acute myocardial infarction, which may also cause swelling of the calves. Some people may have a history of heart failure, renal insufficiency, acute myocardial infarction, relatively speaking, will also appear in the case of swelling of the calves; there are also some people may have fatigue, constipation, then this situation is highly considered to be due to hypothyroidism caused by the swelling of the calves.