When breast cancer metastasizes to the thoracic lumbar spine, the following aspects of treatment can be chosen: 1. Surgery: Breast cancer metastasis to the thoracic lumbar spine will cause damage to the bone. If fracture occurs or the risk of fracture is high, surgical treatment in orthopedics is needed. 2. Anti-tumor treatment: patients with breast cancer metastasis to the thoracic lumbar spine need to choose chemotherapy, radiotherapy, endocrine therapy, targeted therapy and other methods under the guidance of doctors and with the combination of breast cancer gene mutation, including HER-2 overexpression, and endocrine therapy indicators. 3. Analgesic treatment: when breast cancer metastasizes to the thoracic and lumbar vertebrae, patients will have pain, and when it is serious, they need to take pain-relieving drugs under the guidance of doctors to improve the quality of life. 4. Anti-bone metabolism treatment: Zoledronic acid and other phosphonate preparations are often applied in clinic to protect bone tissue and reduce bone destruction. It is recommended that patients go to the hospital in time to receive standardized treatment.