Esophageal cancer of 6 centimeters does not clarify the clinical staging of the patient. Esophageal cancer is a common malignant tumor of the digestive tract. Its clinical staging is mainly based on tumor TNM staging, in which T represents the degree of invasion of primary tumor lesion, N represents lymph node metastasis and M represents distant metastasis. Primary tumor foci (T): T1 stage tumor invades the mucosal layer, T2 stage tumor invades the intrinsic muscular layer, T3 stage invades the esophageal fibrous membrane, and T4 stage invades the adjacent tissues and organs. Lymph node metastasis (N): no lymph node metastasis at stage N0, 1-2 regional lymph node metastasis at stage N1, 3-6 regional lymph node metastasis at stage N2, and more than 7 regional lymph node metastasis at stage N3. Distant metastasis (M): no distant de-metastasis in stage M0 and distant metastasis in stage M1. In summary, according to TNM staging requirements, 6 centimeters of esophageal cancer cannot determine the clinical staging of esophageal cancer patients. However, when the tumor is large, it is easy to invade the esophageal tissue structure, and the clinical staging is mostly in the middle or late stage. It is recommended that patients should follow the specialist’s advice to further standardize the diagnosis and treatment, to clarify the specific stage of esophageal cancer and receive treatment as early as possible. At the same time, patients should have a regular routine, ensure enough sleep every day, and avoid overwork and cold.