Uremia may lead to anuria if kidney function is severely impaired. A 24-hour urine output of less than 100ml is called anuria. Under normal circumstances, glomerular filtration produces 180L of primary urine per day, and after reabsorption in the renal tubules and collecting ducts, about 1.5L of final urine is formed. In uremia patients, renal function is severely impaired, urine production and excretion is impaired, and oliguria or anuria may occur. Patients with uremia have decreased renal excretory and metabolic functions, which may result in disorders of water-electrolyte and acid-base balance, accumulation of toxins, renal anemia, and renal bone disease. Diagnosed with uremia, early renal replacement therapy is required, specifically including hemodialysis, peritoneal dialysis and kidney transplantation. Uremic patients, whether they have urine or not, should go to the hospital in time and be treated under the guidance of professional physicians.