The appearance of fever in herpes zoster does not mean that the condition has worsened, caused by the patient’s own resistance is low. Herpes zoster is caused by varicella-zoster virus infection of the human body, the primary infection manifested as chickenpox, chickenpox healed, the virus can be latent in the nerve cells. When the varicella-zoster virus latent in the nerve cells is reactivated, shingles can appear. Herpes zoster can be preceded by systemic symptoms such as fever, malaise, and loss of appetite, which are the pre-symptoms of herpes zoster, followed by a skin rash that is distributed in bands along the nerves. Some patients may also have persistent fever even after the rash comes out. The patient’s resistance is relatively low, the virus reproduces in large quantities, and the virus enters the bloodstream to cause viremia, leading to fever. When herpes zoster secondary bacterial skin infection, can also lead to fever symptoms, represents the emergence of a new condition, need to be anti-infective symptomatic treatment. With the appearance of shingles, it is recommended to seek medical attention and standardized treatment.