There are many kinds of antihypertensive drugs, how to choose the elderly? Today introduces a few basic principles for choosing antihypertensive drugs. 1. Try to use long-acting antihypertensive drugs. Long-acting antihypertensive drugs have a long half-life, and most of them can be taken once a day, which is not only convenient but also more stable. Angiotensin II receptor blockers (ARBs) are long-acting drugs, and angiotensin-converting enzyme inhibitors (ACEIs) are long-acting drugs except captopril and enalapril. Calcium channel blockers (CCB), such as amlodipine and lacidipine, are also long-acting drugs. If short-acting drugs are made into extended-release or controlled-release tablets, they can also achieve the effect of long-acting antihypertensive effect, such as nifedipine controlled-release tablets and felodipine extended-release tablets. 2. Pay attention to the adverse reactions and contraindications of drugs. For example, CCB drugs can often cause increased heart rate, double lower extremity edema, therefore, for patients with fast heart rate or double lower extremity edema, the use of attention should be paid to, it is best to switch to other antihypertensive drugs. The contraindications of the drug should also be borne in mind, otherwise it is easy to aggravate the condition, such as patients with bronchial asthma, beta-blockers should be prohibited. 3. Individualization of antihypertensive program. Choose the antihypertensive program according to the characteristics of your own hypertension and the underlying disease. For example, patients with fast heart rate and coronary heart disease can choose β-blockers; patients with heart failure can choose diuretics, ACEI or ARB and β-blockers; patients with diabetes mellitus and chronic kidney disease should choose ACEI or ARB; patients with cerebrovascular disease (cerebral infarction, cerebral hemorrhage) with hypertension can choose ARB or long-acting CCB. 4. Combined antihypertensive treatment. For patients with grade 2 or above (≥160/100mmHg) hypertension, a combination of two antihypertensive drugs can be used at the beginning, which is conducive to the blood pressure reaching the target value in a shorter period of time, and also helps to reduce the adverse reactions. The above are some basic principles, the development of a reasonable antihypertensive program requires the participation of a professional physician, it is recommended that elderly patients and physicians to develop a personalized antihypertensive program, in order to better achieve the blood pressure target.