Blisters are medically referred to as blisters. Small blisters on the soles of the feet may be caused by daily friction, athlete’s foot or eczema, etc. Depending on the situation, you can take appropriate treatment, such as picking the blisters, applying medication or oral medication and other ways of treatment. 1. Daily friction: Wearing improperly sized shoes for a long period of time can cause blisters to form on the feet due to friction and irritation, and the symptoms of peeling appear. You can use a sterile syringe to break the blisters, and try to wear relatively loose or comfortable shoes to minimize the physical friction caused by wearing shoes. 2. Tinea pedis: mainly caused by fungal infection, can be transmitted between people through direct or indirect contact, manifested as blisters, flaking, itching and other symptoms of foot skin. Fungal infections can be prescribed topical antifungal ointment, such as naftifine ketoconazole cream, oxiconazole nitrate cream, etc., so as to alleviate the purpose of the symptoms. If necessary, combined with oral medication such as fluconazole. 3. Eczema: Eczema may be triggered by excessive sweating of the feet and irritation of the skin by the sweat, resulting in blistering and peeling of the feet. You can apply zinc oxide ointment under the guidance of a doctor, and if necessary, apply corticosteroid hormone ointment, such as mometasone furoate ointment, halometasone ointment and other ointments. You can also take oral loratadine as an anti-allergy treatment. The appearance of small blisters on the soles of the feet and peeling of the skin may also be other causes, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor to clarify the cause of the disease, and targeted treatment or treatment. The above drugs should be used under the guidance of a doctor.