Splenectin can treat urticaria, but it belongs to immunomodulatory drugs, which are auxiliary drugs that can regulate the immune function of the body. Urticaria is mainly caused by hypersensitivity reactions and immune disorders, but it mainly requires anti-allergy medication, such as chlorpheniramine maleate tablets, cycloheximide hydrochloride tablets, levocetirizine hydrochloride capsules, loratadine citrate capsules, desloratadine capsules, loratadine capsules or olopatadine hydrochloride tablets, etc. And urticaria can be treated with topical glycolate lotion. Also, if the hives are severe, you can inject chlorpheniramine maleate injection, or even dexamethasone injection or compound betamethasone injection. If the patient is still not relieved, he can also be sedated with compound glycyrrhizic acid monoammonium S sodium chloride injection or injectable compound glycyrrhizin injection, or even methylprednisolone injection.