With the popularity of knowledge on pregnancy preparation, many people know that women need to take folic acid supplements during the first 3 months of pregnancy to prevent fetal neurological developmental disorders, but the same need for men to take folic acid supplements during this period is often overlooked. Folic acid is a water-soluble B vitamin, and a mother-to-be’s need for folic acid during pregnancy is four times higher than normal. Folic acid deficiency at this time can lead to fetal neural tube abnormalities and may also cause miscarriage. By the middle and late pregnancy, folic acid deficiency makes pregnant women prone to placental abruption, gestational hypertension syndrome, intrauterine growth retardation, premature birth and low birth weight of the fetus, and the growth and intellectual development of the child after birth will be affected. In addition, it is recommended that the father-to-be should also take folic acid supplements 3 months before his wife prepares for pregnancy. Most men tend to have the habit of smoking and drinking alcohol, which easily causes nutrient loss. At the same time, men prefer meat in their diet and eat less vegetables and fruits, which, together with social pressure and environmental pollution, have reduced the quantity and quality of sperm. Studies have shown that with an average daily intake of 722~1500 micrograms of folic acid for men before conception, the sperm risk factor will be reduced by 20%~30%. Therefore, it is necessary for husbands to take folic acid supplementation before conception, in addition to the basic abstinence from smoking and alcohol. Generally speaking, men can take more green leafy vegetables, fruits and beans for folic acid supplementation. However, it is necessary to consider taking a daily supplement with an additional intake of 0.4 mg of folic acid if the following conditions exist: frequent alcohol consumption, many men often need to go out to socialize and drink, but excessive alcohol intake can hinder the absorption of folic acid by the body. Taking certain medications, such as sulfonamides, sleeping pills, sedatives, aspirin, etc. may affect the absorption of folic acid. If you are taking the above mentioned medications, it is recommended to increase the intake of folic acid under the guidance of your doctor.