Simvastatin and Aspirin Combination Side Effects

Simvastatin and aspirin both do not interact with each other, they can be taken together, and the side effects of both should be the adverse reactions of each. Simvastatin is a lipid-lowering medication that is mainly used for hypercholesterolemia and coronary heart disease. Simvastatin is used to adjust the low-density lipoprotein drugs, usually taken at bedtime, while aspirin is used for antipyretic, analgesic, anti-inflammatory, anti-rheumatic, anti-thrombotic drugs, usually in the morning on an empty stomach, so the two are generally not combined, and the two do not interact. Upper and lower gastrointestinal discomfort, increased risk of bleeding, and, in severe cases, acute kidney failure and kidney injury may occur while taking aspirin. Upper respiratory tract infections, interstitial lung disease, abdominal pain, constipation and, in severe cases, allergy and lupus erythematosus-like syndrome may occur with simvastatin. Simvastatin is contraindicated in people who are allergic to any of its components; active hepatitis or unexplained persistent elevation of serum aminotransferases; and is contraindicated in combination with the tetralin-based calcium channel blocker mibefradil. Aspirin is contraindicated in people who are allergic to aspirin or other hydrochloride drugs and who may cause asthma, as well as people with acute gastrointestinal ulcers, bleeding disorders, severe hepatic, renal, or cardiac failure, or people who are on methotrexate. If adverse reactions occur, seek medical attention as soon as possible.

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