Chemotherapy is a common systemic treatment for malignant tumors, and generally intravenous chemotherapy and oral chemotherapy are used more frequently. The first reaction of chemotherapy may not be too great, because chemotherapy is usually applied as adjuvant chemotherapy after surgery, and the patient’s physical condition may be better, so there may be no obvious increase of accumulation of chemotherapy drugs in the body for the first time. Before chemotherapy, there are also some antiemetic and reactive drugs, and most of them may be tolerated without significant reactions when they are first administered with chemotherapy drugs. However, some reactions may appear 1-2 days after the end of chemotherapy, the most common being gastrointestinal reactions, such as nausea, vomiting, etc. Some delayed reactions may appear only a week after chemotherapy. In addition, there is also a kind of bone marrow suppression, resulting in a decrease in white blood cells, anemia, etc. Therefore, it is necessary to monitor the blood routine during chemotherapy, and it is necessary to apply symptomatic treatment such as whitening drugs.