Chemotherapy, as a common anti-tumor treatment method, is widely used in clinical practice. Whether it is intravenous chemotherapy or oral chemotherapy, the side effect of hair loss may occur, which is a toxic side effect of chemotherapy drugs. Generally, this kind of hair loss is reversible, that is, after the chemotherapy course, as long as the nutrition can keep up, the hair will grow out again. The new hair may look better, so don’t worry too much. In addition, this kind of hair loss is also related to the chemotherapy regimen, some chemotherapy drugs will be more obvious hair loss reaction, such as docetaxel, paclitaxel-type drugs. There are also some drugs that cause hair loss reactions that are not too severe, such as fluorouracil, pemetrexed, etc. Therefore, the chemotherapy regimen and the course of chemotherapy have different effects on hair loss.