Cytomegalovirus antibodies are divided into IgM and IgG, with IgM being a marker of recent infection and IgG being a marker of previous infection. If the cytomegalovirus antibody is IgG positive, it is indicative of a previous cytomegalovirus infection and does not require special management. If the cytomegalovirus antibody is IgM positive and there are clinical signs of an associated viral infection or a combination of liver function impairment, such a patient will require antiviral therapy. The drug of choice for antiviral therapy is ganciclovir, which is given for about 2-4 weeks. For most adults and immunocompetent children, cytomegalovirus infection is often self-limiting and will resolve spontaneously without specific treatment.