Causes of a burst of stabbing pain in the thigh include: thigh muscle injury, chronic strain, muscle and nerve compression can lead to pain, it is recommended to identify the cause of treatment. 1. Thigh muscle injury: excessive exercise or inadequate preparation before exercise causes muscle strain, contusion and other pain, can be treated by rest, hot compresses, massage and other ways. 2. Chronic strain injury: Long-term heavy labor or prolonged standing, walking, etc. leads to aseptic inflammation of the muscle and then cause pain. When the pain is severe, you can take ibuprofen, celecoxib and other drugs to relieve pain. 3. Nerve and muscle compression: seen in the pear-shaped muscle syndrome, lumbar disc herniation and other compression of the sciatic nerve pain, severe cases of surgical treatment. A burst of thigh pain can also be seen in tumor compression, femoral head lesions, etc., should go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, give targeted treatment or treatment. All of the above drugs should be taken under the guidance of a professional physician.