As gingivitis and periodontitis are inflammatory reactions occurring in the gum and periodontal area, so in the acute inflammatory stage can be under the guidance of a doctor, the application of antibacterial drugs to kill pathogenic bacteria in the oral cavity, which can to a certain extent relieve the pain, redness and swelling symptoms caused by oral inflammation. In addition, you can also use painkillers to relieve pain and reduce the patient’s discomfort, but oral medication can only achieve the role of symptom relief. The key to eradicating gingivitis and periodontitis lies in periodontal treatment, that is, the thorough elimination of dental calculus, plaque and other irritants around the teeth, so you need to go to a professional dental hospital for treatment. I, antibiotics: 1, nitroimidazole: clinically used metronidazole, tinidazole, etc., more suitable for gingivitis, periodontitis caused by anaerobic bacteria, less adverse reactions, but patients suffering from central nervous disease can not be used; 2, penicillin: clinically used penicillin, amoxicillin, etc., when used in combination with metronidazole, can increase the anti-inflammatory effect of metronidazole, but some patients are allergic to penicillin, before using 3, tetracyclines: clinically used are tetracycline, minocycline, etc., for broad-spectrum antibacterial drugs, wider than metronidazole, but easy to cause dental damage, children and pregnant women can not be used; 4, macrolides: clinically used are roxithromycin, azithromycin, etc., the advantage is less side effects, low systemic toxicity, but may cause nausea, vomiting and other uncomfortable symptoms. Second, non-steroidal anti-inflammatory drugs: clinically used are ibuprofen, aspirin, acetaminophen tablets, etc., can relieve the pain caused by gingivitis, periodontitis, generally moderate oral intake and will not produce side effects on the body. However, it is not recommended to take large amounts to avoid drug dependence. Gingivitis and periodontitis are often caused by infection due to calculus, food residues, damage to restorations, etc. The effect of using drugs is limited and is mostly used during the acute inflammatory phase of periodontitis or when gingivitis is accompanied by a systemic inflammatory response. After the acute inflammatory period of gingivitis and periodontitis, clinical treatment such as scaling and subgingival scraping are often used to eradicate the cause of the disease, which is more effective.