Children coughing after five o’clock at night may be gastroesophageal reflux, whooping cough syndrome, cough variant asthma, upper airway cough syndrome factors. 1. Gastroesophageal reflux: the baby due to the digestive tract development is not yet perfect, after eating milk, such as caused by reflux, can lead to the baby cough, usually seen after eating milk. 2. Pertussis syndrome: the disease is mainly caused by pertussis bacillus acute respiratory infectious diseases, the child will appear paroxysmal cough, accompanied by chicken-like echoes, usually accompanied by fever and other symptoms. Often manifested in the evening, night cough obvious. 3. Cough variant asthma: and genetic, environmental and other factors, the child can appear paroxysmal cough, often cough for a long time. The cough is more pronounced in the evening and early morning. 4. Upper airway cough syndrome: when the nasal cavity, sinuses in the state of chronic inflammation, inflammation parts of the purulent secretions produced by the nasal reflux, commonly found in the position change, and accompanied by coughing up phlegm, pharyngeal itching, pharyngeal foreign body sensation. If the baby repeated cough, parents are advised to take the child to the hospital in time, under the diagnosis of the doctor, according to the specific conditions of the child, to take targeted treatment.