The staging of breast cancer is decided according to the international TNM staging, ki67 is only an immunohistochemical index, not a key factor to decide the staging. ki67 is a kind of nuclear protein, its function is to indicate the proliferation index of the cells, generally speaking, the lower the value of ki67 means the lower the proliferation index of the tumor, the better the prognosis is, and the possibility of metastasis or recurrence is lower. The international TNM standard is used for the staging of breast cancer, T refers to the size of the tumor, N refers to whether there is lymph node metastasis, N0 means no lymph node metastasis, M refers to whether there is distant metastasis, M0 means no distant metastasis. The specific staging should be timely medical treatment to receive examination, and the pathology department will make professional judgment. Breast cancer ki67 for 5% to timely medical treatment, receive treatment, follow medical advice.