Possible causes of headache and eye distension during menstruation include migraine, excessive water intake, endocrine changes and so on. 1. Migraine: due to the sudden drop of estrogen in the body, the blood vessels in the brain can not adapt to the sudden change of endocrine hormones, and the contraction and diastolic function of the blood vessels is impaired, then the patient is prone to headache and eye swelling during menstruation. 2. Drinking too much water: it is easy to change the hormone level in the body, which affects the normal regulation of the nervous system, and it is easy to show headache and eye swelling during menstruation. 3. Endocrine changes: During menstruation, the serum estradiol concentration in the blood decreases, causing endocrine disorders and changing the tone of blood vessels, and women who are more sensitive may experience headaches and eye swelling during menstruation. There may be other conditions associated with menstrual headache and distended eyes, so you can go to the hospital for relevant examinations to clarify the situation and take appropriate measures.