Clinicians have designed the “three, three, three” questions for self-diagnosis, which can initially determine whether you are suffering from dryness syndrome. 1. Three questions for dry mouth 1. 2.When you eat dry food (such as cookies), do you have to use water to help you swallow? 3.Are you awakened by dry mouth more than 3 times/night after sleeping? Second, the three problems of dry eyes 1, there is a feeling of dry eyes for more than 3 months? 2.Without trachoma and other obvious eye diseases, do you often have a gritty feeling in your eyes? 3.Do you have to use tear substitutes (eye drops) more than 3 times a day to moisten your eyes? Auxiliary three questions 1.Is there any unexplained joint pain? 2.Do you have recurrent or persistent enlargement of salivary glands (such as parotid glands)? 3.Do you have tooth decay or tooth loss rapidly in the last few months or years? In the above three questions, if one of the answers in the dry mouth series or dry eye series is yes, plus one of the answers in the auxiliary three questions is “yes”, then we can suspect the possibility of dry syndrome; if more than one answer in each of the three question series is “yes”, then If there is more than one answer of “yes” in each of the three question series, then it is highly suspected to be dry syndrome, and you should go to the rheumatology department of the regular hospital for examination and diagnosis in time.