Depending on the nature of the pain and the accompanying symptoms, it may be kidney stone, acute pyelonephritis or lumbar muscle strain disease, which requires appropriate treatment. 1. If the pain is paroxysmal or continuous colic, accompanied by percussion pain at the angle of the ribs and spine, there is a high suspicion of kidney stones. Then you need to go to the hospital as soon as possible for the appropriate auxiliary examination to clarify the condition. If it is a kidney stone, renal ultrasound can be clear, according to the location and size of the stone needs to be lithotripsy, while taking pain-relieving and anti-inflammatory drugs. 2. If there is pain on both sides of the kidney, accompanied by frequent urination, urgency, painful urination and hematuria, acute pyelonephritis is highly suspected, and antibacterial and anti-inflammatory drugs should be taken. 3. If the nature of the pain is bilateral dull pain or hidden pain, with or without changes in position, activity after the aggravation of the lumbar muscle strain disease, need to bed rest, take pain medication, but also auxiliary Chinese medicine acupuncture, massage and other operations to relieve the pain symptoms, if the pain is more severe impact on daily life, but also can be injected with local closed therapy. Pressure pain on both sides of the kidney area can be considered a variety of diseases, need to carry out the appropriate examination to be able to treat the symptoms. It is recommended that the patient go to the hospital as soon as possible for ultrasound of the kidney area, CT, urine routine and other tests to clarify the condition, and take medication under the guidance of the doctor to relieve the pain symptoms.