The symptoms of ceftriaxone allergy are relatively numerous and can include dizziness, headache, nausea, vomiting, rash, and even severe spasms that can affect the bronchial tubes, further shock and a host of other symptoms. Once cephalosporin is allergic, it is very serious and can be life-threatening in severe cases. Therefore, a rigorous allergy test must be performed before administering cephalosporin. If the skin test is negative, cephalosporin can be administered. If there is a previous allergy to cephalosporin, it is not recommended to perform cephalosporin dosing. Ceftriaxone is a third-generation cephalosporin antibiotic with significant therapeutic effects and is widely used in clinical practice at a relatively moderate price. At the same time, during the use of cephalosporin, alcohol must be strictly avoided to avoid triggering disulfiram reaction.