Low fasting blood glucose and high postprandial blood glucose indicate that the patient may have basal pancreatic function basically normal, but postprandial insulin function decreases and the peak of plasma insulin secretion is delayed, resulting in postprandial hyperglycemia. Treatment should focus on promoting postprandial insulin secretion and lowering postprandial blood glucose, and the treatment methods include medical nutrition therapy, exercise therapy and drug therapy. 1. Medical nutrition therapy: control the total energy intake, obese people should control their weight and lose weight. Reasonable distribution of nutrients, ensure the intake of carbohydrates (50%~60%), and try to eat foods with low glycemic index. Ensure protein intake, fat intake, while choosing foods rich in dietary fiber, which can delay food absorption and reduce postprandial blood sugar. 2. Exercise therapy: Under the guidance of a physician, regular and appropriate exercise should be carried out in a gradual manner and persisted for a long period of time. It is recommended that 150 minutes of moderate-intensity exercise per week, and appropriate exercise one hour after meal is conducive to postprandial blood glucose control. 3. Drug therapy: drugs commonly used to reduce postprandial blood glucose include non-sulfonylureas, such as Repaglinide, etc., which can reduce postprandial blood glucose by stimulating the secretion of insulin in the early phase; α glucosidase inhibitors, such as Acarbose, etc., which can reduce postprandial blood glucose by delaying the absorption of carbohydrates; and short-acting insulin, which is injected subcutaneously with a suitable dosage of insulin before meals to control postprandial blood glucose. Patients with low fasting blood glucose and high postprandial blood glucose are recommended to visit the endocrinology department to monitor their blood glucose and use reasonable medication under the guidance of physicians.