Orlistat can be taken during menstruation. This drug is mainly used clinically for weight loss, such as diabetes, hypertension or dyslipidemia due to the corresponding dangerous conditions of obesity, and can be given under the guidance of a doctor for weight loss. This drug may cause an increase in the number of stools, nausea, vomiting and other clinical symptoms, upper or lower respiratory tract infections and headaches, and may cause menstrual disorders, but it does not affect menstruation when taken during menstruation. If eaten for a long time, when the weight loss is significant, it may lead to menstrual disorders. Therefore, once menstrual disorders occur, it is recommended to seek medical advice to see if the medication can be stopped for treatment.