Disproportion of the main pulmonary arteries can usually be tested without amniocentesis in the first place, but if there are obvious chromosomal abnormalities, then amniocentesis is recommended. Disproportion of the main pulmonary arteries is initially considered to be caused by poor development of the fetal heart and blood vessels. Probably because the fetus is so small, the disproportion of the main pulmonary artery does not indicate many problems, and the condition usually disappears before birth as the fetus develops. And amniocentesis does carry some risk, so if there are no obvious malformations of the heart at present, amniocentesis can usually be avoided first. However, if the main pulmonary artery disproportion causes chromosomal abnormalities in the fetus, or if there is a relatively high chance of intrauterine infection, then amniocentesis is recommended for testing. Patients with aortopulmonary disproportion need to pay attention to rest and nutritional balance, always observe the condition of the fetus, and if it is necessary to do amniocentesis, it must not be avoided because of the risk, so as to avoid adverse consequences.