Immunoglobulin E 148IU/ml is higher than the upper limit of the normal reference range, but you can’t judge the severity of the patient’s condition only from the immunoglobulin E test results, but rather, you have to analyze it comprehensively in terms of the causes of the immunoglobulin E increase and the patient’s comprehensive situation, etc. The common causes of the immunoglobulin E increase are hypersensitivity diseases, parasitic infections and so on. Immunoglobulin E is lgE, and the normal reference range of immunoglobulin E is below 100IU/ml, and 148IU/ml is higher than the upper limit of its reference range. Immunoglobulin E is closely related to type I hypersensitivity reactions, such as exogenous asthma, allergic rhinitis, etc. In addition to this, elevated immunoglobulin E may be seen in parasitic infections, drug-induced interstitial pneumonitis, and lgE-type multiple myeloma. Different diseases causing elevated immunoglobulin E and the severity of the patient’s condition also differ greatly, so it is not possible to generalize. For example, although allergic diseases such as allergic rhinitis and exogenous asthma are incurable, they can be prevented from onset and the symptoms can be controlled by avoiding contact with the allergens, and interstitial pneumonitis caused by medications can be cured after stopping the suspected medications in a timely manner. It is recommended that patients with immunoglobulin E148IU/ml should go to the Department of Infectious Diseases, Department of Otorhinolaryngology and other related departments in regular hospitals for further diagnosis.