Uremic patients generally do not have physical pain, late may appear bone pain, joint pain, headache, etc., the following specific analysis. Uremia is the end stage of chronic renal failure, at this time patients generally have symptoms such as elevated blood pressure, a small amount or no urine, if patients with elevated blood pressure can appear headache, at this time should be actively given to control blood pressure, blood pressure back to normal headache natural relief. If the patient has bone pain and joint pain, the cause may be due to calcium deficiency or disorder of calcium and phosphorus metabolism, and the treatment should be calcium supplementation, such as taking calcium carbonate, osteopontin and other drugs, and taking drugs to lower phosphorus for treatment.