It is possible to have intercourse in uremia, which is the end stage of kidney disease and the ultimate regression of many kidney diseases, representing a serious decline in kidney function: renal failure. This is when renal replacement therapy is needed, that is, hemodialysis and peritoneal dialysis treatment, but intercourse has little effect on the disease. After the development of uremia, there may be a loss of libido, which affects the quality of life, but there is nothing wrong with intercourse. If you are a male patient, you can even have children; if you are a female patient, pregnancy and childbirth are not recommended because it will affect the fetus, and the probability of malformation or miscarriage is very high. After the emergence of uremia, first of all, regular dialysis treatment is necessary to remove excess water and toxins from the body; secondly, it is also necessary to regularly apply medication, such as erythropoietin, iron and calcium to improve the quality of life.