In pregnant women with elevated total bile acids, the first step should be to improve the relevant auxiliary examinations to further clarify the specific cause of the problem and to treat the cause to achieve better results. Patients who ate a lot of high cholesterol food in a short period of time before the examination are recommended to have a review at a later date. If the review is normal, it is considered to be caused by dietary factors and should be avoided. It is also recommended to eat foods rich in high protein and vitamins, such as soy products, dairy products, fish, and fresh fruits and vegetables during pregnancy. If there is underlying liver disease such as viral hepatitis or cirrhosis before pregnancy, it may be related to these underlying diseases and care should be taken to give liver-protective treatment. If there is a significant elevation of hepatitis B viral DNA, oral antiviral drugs such as lamivudine should also be administered promptly and relatively safely. In case of intrahepatic cholestasis during pregnancy, high priority should be given to the active application of vitamin energy combination to reduce bile acids, and oral medications such as ursodeoxycholic acid, adenosylmethionine, and dexamethasone can also be considered for treatment. For pregnancies over 36 weeks, the fetal lungs are mature and the general condition of the pregnant woman is good, a cesarean section should be performed in time to end the pregnancy.