Radiotherapy for rectal cancer generally does not cause numbness of hands and feet, and it is necessary to clarify the cause of the disease and receive standardized treatment. Generally speaking, rectal cancer radiotherapy will not cause numbness of hands and feet. Numbness of hands and feet after radiotherapy for rectal cancer patients may be caused by the following reasons: 1. Some chemotherapeutic drugs for rectal cancer have certain neurotoxicity. When used in large quantities or for a long period of time, the neurotoxicity accumulates continuously, which may lead to peripheral nerve damage, resulting in numbness of hands and feet, which can be relieved by some patients on their own. If the numbness of hands and feet is more serious, under doctor’s guidance, the patient can take nerve-nourishing drugs, and if necessary, the chemotherapy program should be adjusted. 2. Part of rectal cancer itself suffers from diabetes mellitus, if diabetic peripheral nerve damage occurs, numbness of limbs, hands and feet will also occur, at this time need to control blood sugar. The numbness of hands and feet caused by cervical spondylosis and lumbar spondylosis needs interventional treatment from cervical spondylosis and lumbar spondylosis. The numbness of hands and feet caused by cerebral infarction needs to be treated for cerebral infarction, and at the same time, neurotrophic drugs should be applied. In addition, in life should pay attention to keep warm, avoid cold water, cold air on the hands and feet of the stimulation and aggravate the numbness of the symptoms, but the specific measures should be combined with their own situation, you should seek the doctor’s professional advice.