The redness and peeling of the skin underneath the lower lip may be considered as perioral dermatitis, seborrheic dermatitis, eczema, etc., which can be treated with oral medication or local topical medication as appropriate. 1. Perioral dermatitis: If local contact with allergic substances or eat allergic food may cause redness and peeling of the skin around the lower lip, allergens should be identified and avoid re-exposure, if necessary, you can apply mometasone furoate, fluorine easy. 2. Seborrheic dermatitis: seborrheic dermatitis occurs in the forehead, nose and mouth and other sebum secretion parts, can be manifested as erythema, pimples, moulting, usually pay attention to facial cleansing, topical pimecrolimus cream, the symptoms of the more serious can be combined with oral medication, such as tanshinone capsule and so on. 3. Eczema: Eczema is a relatively common skin disease, is a chronic inflammation of the skin, you can strengthen the basic moisturizing skin care, first coated with weak hydrocortisone treatment, for the more obvious symptoms of the duration of a longer period of time you can use tretinoin, betamethasone and other drugs. Redness and peeling underneath the lower lip should go to the hospital by the doctor to clarify the cause of the disease, standardized treatment, the above drugs should be used in accordance with the doctor’s instructions.