The causes of swollen and pus-filled hands and hard lumps after a barb is pulled out include inguinitis, nail root inflammation, etc., which can be eliminated through medication and surgical treatment. 1. Nail groove inflammation: after pulling out the barbs, if you don’t disinfect them in time, it is easy for pathogenic microorganisms to become infected, showing inflammation of the tissues around the nails. For this case, it is recommended to inject antibiotics intramuscularly to carry out treatment, commonly cephradine, penicillin and so on. If necessary, incision and drainage is also needed in order to eliminate the abscess hard lump as soon as possible. 2. Inflammation of the nail root: If the impingement is at the root of the nail, the problem of pathogenic bacterial infection can also occur. To face this problem, cefixime can be taken orally to fight the inflammation. If the effect of conservative treatment is not good, it is recommended to timely surgery, and in serious cases, even need to remove the necrotic tissue. Barb pulling out the hand swollen pus into a hard lump indicates that the condition is more serious, you should seek medical examination as soon as possible, and follow the doctor’s instructions for treatment, so as not to delay the condition.