In modern society, due to study and work pressure, some babies are not breastfed or only partially breastfed after birth and need milk substitutes, the most important of which is milk, however, some babies do not adapt to milk and develop milk protein allergy. What are the signs of milk protein allergy in babies? 1, gastrointestinal tract: repeated vomiting, diarrhea, constipation, perianal rash, blood in the stool. In severe cases, growth and development are impaired and there is prolonged or medium to large amount of blood in the stool, resulting in decreased hemoglobin and iron deficiency anemia. Allergic colitis in some babies; 2. Skin: eczema (tinea cruris), erythema, rashes, angioedema; 3. Respiratory: non-cold runny nose, chronic cough and wheezing; 4. General: persistent crying (intestinal cramps), greater than or equal to 3 hours/day, greater than or equal to 3 times/week, lasting greater than or equal to 3 weeks. How to determine baby’s milk protein allergy? When a cow’s milk-eating baby shows the above symptoms and milk protein allergy is suspected, the following tests can be done to determine whether the baby is allergic to cow’s milk protein: 1) skin prick test; 2) serum milk-specific IgE antibody measurement; 3) milk avoidance test (the above symptoms will be relieved or disappear after stopping all foods containing milk), or oral milk provocation test (the above symptoms will reappear or worsen after oral milk consumption). What should I do if my baby is allergic to milk protein? The best treatment for cow’s milk protein allergy is to avoid cow’s milk protein and to give hypoallergenic formula replacement therapy to provide your baby with the necessary nutrients for growth and development. When milk protein allergy occurs in breastfed babies, the mother should continue breastfeeding and avoid milk and its products for at least 2 weeks; for some babies with allergic colitis, the mother should continue avoiding milk and its products for 4 weeks. If the mother avoids milk and its products, the baby’s symptoms improve significantly, the mother can gradually add milk, if the symptoms do not reappear, you can resume a normal diet; if the symptoms reappear, the mother should avoid milk and its products during breastfeeding, and after the baby is weaned to give deeply hydrolyzed protein formula or amino acid formula instead. When milk protein allergy occurs in formula-fed babies, babies younger than 2 years old should completely avoid foods and formulas containing milk protein and replace them with hypoallergenic formulas, such as partially hydrolyzed formulas, deeply hydrolyzed protein formulas, and in severe cases, amino acid formulas; when milk protein allergy occurs in babies older than 2 years old, the transition to complementary foods with rich food sources can meet the normal growth and development needs of the baby. The baby’s normal growth and development needs can be met, so a milk protein-free diet can be carried out. It is not recommended to give milk protein allergic babies to eat other animal milk, such as goat’s milk, etc. It is also not recommended to give milk protein allergic babies to eat soy milk, mainly because of nutritional factors and the impact of cross allergic reactions. 3. For babies with severe milk protein allergy, if the symptoms are still obvious after taking the above measures, symptomatic treatment should be carried out under the guidance of a doctor. Commonly used drugs include epinephrine, glucocorticoids, antihistamines, etc. Short-term use can rapidly improve the symptoms and there are not too many side effects, so don’t worry too much.