Every day in the outpatient clinic, we come across children with cow’s milk protein allergy, including infants, toddlers, and school-age children, with infants and toddlers under the age of 6 months being the most common. The main symptoms are severe eczema, diarrhea, abdominal pain and crying after eating milk, bloating, vomiting, nasal congestion, stools mixed with blood, and slow weight gain. In older children, abdominal pain and diarrhea occur after drinking milk. After oral medication is not obvious, some repeated oral anti-inflammatory drugs, or even intravenous infusion, not only bad but the symptoms worsen, which reminds us to pay attention to exclude the possibility of milk protein allergy. In addition to milk, there are eggs, fish, shrimp, wheat, peanuts and so on. However, due to the limitations of pediatric allergen detection difficulties, food allergies are difficult to distinguish. My clinical experience is to first stop all anti-inflammatory drugs and antidiarrheal drugs, stop drinking milk protein, small infants fed amino acid formula alternative diet, older children eat a single food (to facilitate the exclusion), if the symptoms gradually improve and then eat ordinary milk symptoms reappear, it is proved to be milk protein allergy. Strict avoidance of the allergic food is the key to treatment, and in the case of breastfed children, the mother is careful not to drink milk products. The mother is careful not to drink cow’s milk products in case of breastfeeding. During the feeding period, the doctor is visited every other month to evaluate the nutritional status and allergy symptoms. The total course of treatment lasts about 3-4 months, with gradual desensitization. Children on amino acid formulas are gradually changed to a deeply hydrolyzed protein formula, then to a partially hydrolyzed protein formula, then to a regular formula, and gradually return to a normal diet. Only when parents recognize and the adverse consequences caused by food allergy, can they allow their children to grow and develop healthily.