Severe hair loss is considered to be related to damaged hair follicle tissue, androgenetic alopecia, baldness, etc. Daily care, topical, oral medication, and physical therapy can be given. 1. Damaged hair follicle tissue: If patients frequently dye or perm their hair, the chemicals inside will cause stimulation to the stem cells in the hair follicles, which will cause patients to lose their hair. Patients should avoid frequent perming or hair coloring, and can use mild non-stimulating, repairing and nourishing shampoo to shampoo, which can play a role in nourishing and repairing the local hair follicles. 2. Androgenetic alopecia: If the parents suffer from androgenetic alopecia, the child may inherit the genes of the parents and suffer from androgenetic alopecia. Men can follow the doctor’s advice to take finasteride for treatment, which can reduce the secretion of androgen, and women can follow the doctor’s advice to take spironolactone, topical minoxidil for treatment, to alleviate the symptoms of hair loss. 3. Patch baldness: it is a kind of immune disorder disease, according to the condition of the use of oral hormones such as prednisone, topical minoxidil combined with helium-neon laser, plum blossom needle and other physical methods of treatment, pay attention to develop a good life style. The problem of serious hair loss should be timely consultation, patients taking drugs should strictly follow the doctor’s advice, not blindly use drugs.