Kidney pain while lying down and no pain while sitting up may be caused by kidney stones, ureteral stones, glomerulonephritis and other diseases. 1. Kidney stones: when the patient suffers from kidney stones, after lying down due to changes in body position, such as repeatedly turning over, kidney stones are easy to move, will cause irritation to the surrounding tissues, lying down kidney pain, sitting without pain phenomenon. 2. Ureteral stones: If patients with ureteral stones lie down, it will easily lead to a further increase in ureteral pressure, ureteral smooth muscle spasm, lying down kidney pain, sitting without pain symptoms. 3. Glomerulonephritis: the onset of glomerulonephritis may be related to genetic factors, infections, metabolic disorders, etc., the patient will appear lying down kidney pain, sitting without pain, accompanied by hematuria, proteinuria, fatigue and other symptoms. When patients have lying down kidney pain, sitting without pain, they should go to the hospital in time for relevant examinations, and standardized treatment under the guidance of the doctor.