Children with persistent fever of about 38 ℃ for four or five days, can be seen in respiratory diseases, digestive diseases and other conditions, what drugs to take need to be decided according to the cause, such as acute upper respiratory tract infection can be taken orally antiviral combinations and other drugs to treat. Fever is a common symptom of childhood, according to the degree of the child’s temperature rise to choose the appropriate way to reduce fever. For babies with a temperature of 38℃, you can use warm water to wipe the baby’s neck, armpits, thighs and other places, or use antipyretic patches and other physical ways to reduce heat treatment. At the same time need to target the original disease for treatment. 1. Acute upper respiratory tract infection: the above phenomenon can occur, may be accompanied by runny nose, nasal congestion and other symptoms. If it is caused by viral infection, it can be treated with oral antiviral combination, if it is caused by bacterial infection, it needs to be treated with anti-infective treatment such as cefaclor, and if it is caused by influenza virus, it can be treated with oseltamivir. 2. Bacterial enteritis: the above phenomenon can also occur, accompanied by vomiting, diarrhea, etc., can use montelukast to stop diarrhea, Clostridium typhimurium bifidum and other probiotics to regulate the intestinal flora, improve intestinal function. At the same time, according to the bacterial culture and drug sensitivity test, choose ceftazidime, meropenem and other drugs to carry out anti-infection treatment. 3. Acute leukemia: the above phenomenon may also occur, may be accompanied by skin and mucous membrane hemorrhages, lymph node enlargement, etc., the treatment requires the use of vincristine and other drugs to carry out chemotherapy and other treatments. The above drugs should be used under the guidance of a physician, and the above phenomenon can be seen in a variety of diseases, which need to be actively consulted and evaluated by specialists for a clear diagnosis and treatment.